Search results for " Large‑scale model"

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On the structural connectivity of large-scale models of brain networks at cellular level

2021

AbstractThe brain’s structural connectivity plays a fundamental role in determining how neuron networks generate, process, and transfer information within and between brain regions. The underlying mechanisms are extremely difficult to study experimentally and, in many cases, large-scale model networks are of great help. However, the implementation of these models relies on experimental findings that are often sparse and limited. Their predicting power ultimately depends on how closely a model’s connectivity represents the real system. Here we argue that the data-driven probabilistic rules, widely used to build neuronal network models, may not be appropriate to represent the dynamics of the …

0301 basic medicineProcess (engineering)Computer scienceScienceModels NeurologicalCellular levelMachine learningcomputer.software_genreArticle03 medical and health sciencesComputational biophysics0302 clinical medicineSettore MAT/05 - Analisi MatematicamedicineBiological neural networkHumansSettore MAT/07 - Fisica MatematicaOn the structural connectivity of large-scale models of brain networks at cellular levelSettore ING-INF/05 - Sistemi Di Elaborazione Delle InformazioniNeuronsMultidisciplinaryNetwork modelsSettore INF/01 - Informaticabusiness.industryQRProbabilistic logicBrain030104 developmental biologymedicine.anatomical_structureMathematical framework Neuron networks Large‑scale model Data‑driven probabilistic rules Modeling cellular-level brain networksMedicineNeuronArtificial intelligencebusinessScale modelcomputer030217 neurology & neurosurgeryScientific Reports
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